What drives me to keep in science is the wonder and creativity that this job ask from me, and also I enjoy being able to have this continuous thinking machine on my mind that brings me to the next question following my answer.
Yesterday was the stem cell awareness day and I am proud how this field blossomed so much in less than 15 years. It is also a blessing to work on an institution that hit the field with two major milestones: the first human embryonic stem cell (hESCs) (Thompson et al., Nature 1998) and the first human induced pluripotent stem cell (iPSCs) (Yu et al., Science 2007).
We are still away for using stem cells as a cure, but what we have right now that is palpable is having iPSCs from patients that help us better understanding what is wrong with the cells and how can we fix it using molecular tools. Indeed we are already entering the area of personalized medicine.
Because science is also an artistic form of expression, I have posted some of my stem cells (iPSCs) that underwent differentiation for forming blood-brain barrier cells. Without any external molecular guidance, one subset of cells decided to become neurons (left side, green depict bIII-tubulin, red nestin), whereas the other set of cells decided to undergo another pathway and to become brain microvascular endothelial cells.
Enjoy the beauty of the stem cell biology.